N,N-DIPHENYLACETAMIDE

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Good factory supply good N,N-DIPHENYLACETAMIDE 519-87-9

  • Molecular Formula: C14H13 N O
  • Molecular Weight: 211.263
  • Vapor Pressure: 5.26E-07mmHg at 25°C 
  • Melting Point: 100-103 °C(lit.)
     
  • Refractive Index: 1.5780 (estimate) 
  • Boiling Point: 130 °C0.02 mm Hg(lit.)
     
  • PKA: -3.21±0.50(Predicted) 
  • Flash Point: 199.7°C 
  • PSA: 20.31000 
  • Density: 1.125g/cm3 
  • LogP: 3.37120 

N,N-DIPHENYLACETAMIDE(Cas 519-87-9) Usage

General Description

N,N-Diphenylacetamide, also known as benzhydrol or DPA, is a chemical compound with the molecular formula C14H13NO. It is a white, crystalline solid that is soluble in organic solvents and insoluble in water. N,N-Diphenylacetamide is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It can also be used as a plasticizer, a fragrance ingredient, and a UV absorber in sunscreen formulations. The compound has been found to have antimicrobial and antioxidant properties and is currently under investigation for its potential use in various medical and industrial applications. However, it is important to handle N,N-Diphenylacetamide with caution as it may be harmful if ingested, inhaled, or in contact with the skin.

InChI:InChI=1/C14H13NO/c1-12(16)15(13-8-4-2-5-9-13)14-10-6-3-7-11-14/h2-11H,1H3

519-87-9 Relevant articles

Hollow fiber liquid-phase microextraction with in situ derivatization combined with gas chromatography-mass spectrometry for the determination of root exudate phenylamine compounds in hot pepper (Capsicum annuum L.)

Sun, Haiyan,Wang, Yan

, p. 5494 - 5499 (2013)

Hollow fiber liquid-phase microextractio...

Preparation and catalytic evaluation of a palladium catalyst deposited over modified clinoptilolite (Pd&at;MCP) for chemoselective N-formylation and N-acylation of amines

Amirsoleimani, Mina,Khalilzadeh, Mohammad A.,Zareyee, Daryoush

, (2020/08/22)

Novel palladium nanoparticles stabilized...

Method for preparing aryl amide compound by catalyzing carbonylation of aryl tertiary amine through metal-free catalytic system

-

Paragraph 0028-0043; 0050-0063; 0066-0067, (2021/08/19)

The invention discloses a method for pre...

Nickel/Photoredox-Catalyzed Methylation of (Hetero)aryl Chlorides Using Trimethyl Orthoformate as a Methyl Radical Source

Kariofillis, Stavros K.,Shields, Benjamin J.,Tekle-Smith, Makeda A.,Zacuto, Michael J.,Doyle, Abigail G.

supporting information, p. 7683 - 7689 (2020/04/22)

Methylation of organohalides represents ...

Direct Synthesis of N,N-Disubstituted Formamides by Oxidation of Imines Using an HFIP/UHP System

Llopis, Natalia,Gisbert, Patricia,Baeza, Alejandro

, p. 11072 - 11079 (2020/10/12)

The straightforward synthesis of N,N-dis...

519-87-9 Process route

Acetanilid
103-84-4

Acetanilid

phenylboronic acid
98-80-6

phenylboronic acid

N,N-diphenylacetamide
519-87-9

N,N-diphenylacetamide

Conditions
Conditions Yield
With ammonium cerium (IV) nitrate; caesium carbonate; In acetonitrile; at 20 ℃; for 40h; Reagent/catalyst; Sealed tube; Irradiation;
78%
With copper diacetate; triethylamine; In dichloromethane; for 48h; Ambient temperature;
59%
With pyridine; copper diacetate; In dichloromethane; at 20 ℃; for 48h;
35 %Chromat.
diphenylamine
122-39-4

diphenylamine

acetyl chloride
75-36-5

acetyl chloride

N,N-diphenylacetamide
519-87-9

N,N-diphenylacetamide

Conditions
Conditions Yield
With iodine; at 20 ℃; for 0.0833333h; Neat (no solvent);
97.58%
With carbon-silica composite from starch (7.5 molpercent SO3H); at 60 ℃; for 0.45h; solvent-free conditions;
96%
In chloroform; at 20 ℃; for 4h;
78%
With pyridine; In dichloromethane; for 1h;
78%
With silica gel; at 20 ℃; for 6.5h; chemoselective reaction; Green chemistry;
72%
In chloroform; at 0 - 5 ℃; for 3h;
70.83%
With ruthenium(III) 2,4-pentanedionate; at 25 ℃; for 24h;
65%
With benzene;
With pyridine; toluene;
With pyridine; dibutyl ether;
With triethylamine; In dichloromethane; at 20 ℃; for 12h;
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 24h;

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