N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE
Contact usTop quality factory supply 20200-22-0 N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE at low price
- Molecular Formula: C8H7F3N2O2
- Molecular Weight: 220.151
- Vapor Pressure: 0.0111mmHg at 25°C
- Melting Point: 73-75 °C(Solv: ethanol (64-17-5))
- Refractive Index: 1.526
- Boiling Point: 262.1 °C at 760 mmHg
- PKA: -3.14±0.25(Predicted)
- Flash Point: 112.3 °C
- PSA： 57.85000
- Density: 1.427 g/cm3
- LogP: 3.25150
N-METHYL-2-NITRO-4-(TRIFLUOROMETHYL)ANILINE(Cas 20200-22-0) Usage
InChI:InChI=1/C8H7F3N2O2/c1-12-6-3-2-5(8(9,10)11)4-7(6)13(14)15/h2-4,12H,1H3
20200-22-0 Relevant articles
Cu-Catalyzed C-H Allylation of Benzimidazoles with Allenes
Dong, Yaxi,Breit, Bernhard
, p. 6765 - 6769 (2021/09/11)
CuH-catalyzed intramolecular cyclization...
C2-Selective Branched Alkylation of Benzimidazoles by Rhodium(I)-Catalyzed C-H Activation
Tran, Ga?l,Confair, Danielle,Hesp, Kevin D.,Mascitti, Vincent,Ellman, Jonathan A.
, p. 9243 - 9252 (2017/09/11)
Herein, we report a Rh(I)/bisphosphine/K...
2-(4-ARYL-1H-IMIDAZOL-1-YL)ANILINE COMPOUNDS
-
Paragraph 0101, (2015/11/27)
The present invention provides compounds...
Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly
Fader, Lee D.,Bethell, Richard,Bonneau, Pierre,B?s, Michael,Bousquet, Yves,Cordingley, Michael G.,Coulombe, René,Deroy, Patrick,Faucher, Anne-Marie,Gagnon, Alexandre,Goudreau, Nathalie,Grand-Ma?tre, Chantal,Guse, Ingrid,Hucke, Oliver,Kawai, Stephen H.,Lacoste, Jean-Eric,Landry, Serge,Lemke, Christopher T.,Malenfant, Eric,Mason, Stephen,Morin, Sébastien,O'Meara, Jeff,Simoneau, Bruno,Titolo, Steve,Yoakim, Christiane
scheme or table, p. 398 - 404 (2011/03/17)
The discovery of a 1,5-dihydrobenzo[b][1...
20200-22-0 Process route
-
-
593-51-1
methylamine hydrochloride
-
-
121-17-5
2-chloro-3-nitro-5-trifluoromethylbenzene
-
-
20200-22-0
α,α,α-Trifluoro-N-methyl-6-nitro-p-toluidine
| Conditions | Yield |
|---|---|
|
methylamine hydrochloride; 2-chloro-3-nitro-5-trifluoromethylbenzene;
In
ethanol;
at 20 ℃;
for 14h;
With
potassium hydroxide;
In
ethanol; water;
at 60 ℃;
|
80%
|
-
-
367-86-2
1-fluoro-2-nitro-4-trifluoromethyl-benzene
-
-
74-89-5
methylamine
-
-
20200-22-0
α,α,α-Trifluoro-N-methyl-6-nitro-p-toluidine
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
dichloromethane; water;
at 20 ℃;
for 14h;
|
|
|
In
ethanol;
Heating;
|
|
|
In
1-methyl-pyrrolidin-2-one; water;
at 20 ℃;
Cooling with ice;
|
|
|
In
dimethyl sulfoxide;
at 20 ℃;
for 3h;
Inert atmosphere;
|
20200-22-0 Upstream products
-
121-17-5
2-chloro-3-nitro-5-trifluoromethylbenzene
-
74-89-5
methylamine
-
367-86-2
1-fluoro-2-nitro-4-trifluoromethyl-benzene
-
300698-92-4
N-methyl-N-[2-nitro-4-(trifluoromethyl)phenyl]acetamide
20200-22-0 Downstream products
-
35203-49-7
N1 -methyl-4-(trifluoromethyl)benzene-1,2-diamine
-
690231-99-3
4-chloro-3-(1-methyl-5-trifluoromethyl-1H -benzoimidazol-2-yl)-phenylamine
-
690231-96-0
2-(2-chloro-5-nitro-phenyl)-1-methyl-5-trifluoromethyl-1H -benzoimidazole
-
690231-92-6
2-chloro-N -(2-methylamino-5-trifluoromethyl-phenyl)-5-nitro-benzamide
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